CURRICULUM VITAE                                                                                          January, 2016
 
ROGER LAUREN LUNDBLAD
Current Position:   Independent Consultant to the Biotechnology/Biopharmaceutical Industry
Concurrent Position: Adjunct Professor of Pathology, University of North Carolina at Chapel Hill
Business Address:
                        P.O. Box 16695
Chapel Hill, NC 27516-6695
919 560 5029(cellular telephone)
WEBSITE: http://www.lundbladbiotech.com
EMAIL:  roger@lundbladbiotech.com.

Education:   B.S. (Chemistry),  Pacific Lutheran University,  Tacoma, Washington
                    Ph.D. (Biochemistry),  University of Washington,  Seattle, Washington

Employment History


2000-Present:

Independent Consultant to the Biotechnology/Biopharmaceutical Industry

2005-2011

Editor-in-Chief, Internet Journal of Genomics and Proteomics

1998-2000:

Director of Science and Technology Development, Baxter Hyland Immuno,
Duarte, CA

1996-2002

Editor-in-Chief, Biotechnology and Applied Biochemistry

1993-1998:

Director of Science and Technology Development, Baxter Healthcare-Hyland Division,
Duarte, CA

1992-1993:

Director of Science and Technology Development, Baxter Healthcare-Immunotherapy Division, Duarte, CA

1991-1992:

Director of Technology Development, Baxter Healthcare-Hyland Biotechnology, Hayward, CA

1991-Present:

Adjunct Professor of Pathogogy, University of North Carolina, Chapel Hill, NC

1988-1991:

Consultant, Baxter Healthcare-Hyland Division, Glendale, CA

1977-1991:

Professor Pathology, Biochemistry and Periodontics, University of North Carolina, Chapel Hill, NC

1985-1988:

Director, Protein Fractionation/Structural Analysis Core Facility, Department of Pathology, University of North Carolina, Chapel Hill, NC

1978-1984:

Associate Director for Administration, Dental Research Center, University of North Carolina, Chapel Hill, NC

1978-1991:

Associate Director for Program Development, Center for Thrombosis and Hemostasis, University of  North Carolina, Chapel Hill, NC

1972-1977:

Associate Professor of Pathology, Biochemistry and Periodontics, University of North Carolina, Chapel Hill, NC

1968-1972:

Assistant Professor of Pathology, Biochemistry and Periodontics, University of North Carolina, Chapel Hill, NC

1966-1968:

Research Associate, Rockefeller University, New York, NY

1965-1966:

Research Associate, Department of Biochemistry, University of Washington, Seattle, Washington

1961-1965:

Research Assistant, Department of Biochemistry, University of Washington, Seattle, Washington

Honors and Special Recognition
     Distinguished Career Award, Center for Thrombosis and Hemostasis,
     University of North Carolina at Chapel Hill, March 1987
     Centennial 100 Alumni, Pacific Lutheran University, Tacoma, WA,
     October, 1990
     Baxter Technical Achievement Award for Development of Generic
     Purification Process for Recombinant Biopharmaceuticals, 1992
     Who's Who in America, 1995 - present
     Baxter Technical Council Member, 1995-2000
     Baxter Science and Technology Award for Human Thrombin Purification. 1995
     Baxter Science and Technology Award for Recombinant Factor VIII, 1995
     Editor-In-Chief, Biotechnology and Applied Biochemistry, 1996 – 2002
     Editor-in-Chief, Internet Journal of Genomics and Protemics,2005-2011
Community Service
    Church Council, Holy Trinity Lutheran Church, Chapel Hill, NC 27514
     High School Football Office, North Carolina State High School Officials Association
     Transportation Board, Town of Chapel Hill
      Board of Directors, Weatherstone Homeowners’ Association

                                                                        PUBLICATIONS

  • Lundblad RL, Davie EW:  The Activation of Antihemophilic Factor (Factor VIII) by Activated Christmas Factor (Activated Factor IX).  Biochemistry 3:1720-1725, 1964.
  • Lundblad RL, Davie EW:  The Activation of Stuart Factor (Factor X) by Activated Antihemophilic   Factor (Activated Factor VIII).  Biochemistry 4:113-118, 1965.
  • Lundblad RL, Stein WH:  On the Reaction of Diazoacetyl Compounds with PepsinJ Biol Chem      244:154-160, 1969.
  • Lundblad RL, Moore S:  Studies on the Solubilization of 2', 3'-Cyclic Nucleotide 3'-Phosphohydrolase from Bovine Brain.  Brain Res 12:227-229, 1969.
  • Pitlick FA, Lundblad RL, Davie, EW:  The Role of Heparin in Intrinsic Blood Coagulation.  J Biomed Mater Res 3:95-106, 1969.
  • Davie EW, Hougie C, Lundblad RL:  Mechanisms of Blood Coagulation," in Recent Advances in Blood Coagulation, ed. L. Poller, J. & A. Churchill Ltd., London, pp. 13-28, 1969.
  • Lundblad RL, Puryear GM:  Human Salivary Coagulant Activity:  The Stimulation by a-Chymotrypsin. Arch Oral Biol 16:985-987, 1971.
  • Lundblad RL:  A Rapid Method for the Purification of Bovine Thrombin and the Inhibition of the Purified Enzyme with Phenylmethylsulfonyl Fluoride.  Biochemistry 10:2501-2506, 1971.
  • Lundblad RL, Harrison JH:  The Differential Effect of Tetranitromethane on the Proteinase and Esterase Activity of Bovine Thrombin.  Biochem Biophys Res Commun 45:1344-1349, 1971.
  • Lundblad RL, Webster WP, Brinkhous KM:  The Effect of Dextrose on Chromatography of Antihemophilic Factor (Factor VIII).  Thromb Res 1:197-200, 1972.
  • Woolweaver DA, Koch GG, Crawford JJ, Lundblad RL:  Relation of Orogranulocytic Migratory Rate to Periodontal Disease and Blood Leukocyte Count:  A Clinical Study.  J Dent Res 51:929-939, 1972.
  • Lundblad RL, Harrison JH, Mann KG:  On the Reaction of Purified Bovine Thrombin with N-Acetylimidazole.  Biochemistry 12:409-413, 1973.
  • Lundblad RL, Bartlett SR, Hornsby TE, Hudson JD, Rose CH:  Immunological Nonidentity of Parotid and Pancreatic Nucleases.  J Dent Res 52:396, 1973.
  • Vogel CN, Parfitt HE, Kingdon HS, Lundblad RL:  Preparation of Modified Bovine Factor VIII with Enhanced Biological Activity Using Insoluble-Trypsin Columns.  Thromb Diath Haemorrh (Stuttg.) 30:229-234, 1973.
  •  Lundblad RL:  Observations on the Hydrolysis of p-Nitrophenyl Acylates by Purified  Bovine Thrombin.Thromb Diath Haemorrh (Stuttg.) 30:248-254, 1973.
  • Lundblad RL, Kingdon HS:  Biochemistry of the Interaction of Bovine Factors XIa and IX.  Thromb Diath Haemorrh (Stuttg.), Suppl 57:315-333, 1974.
  • Chandler DC, Silverman MS, Lundblad RL, McFall WT:  Human Parotid IgA and Periodontal Disease.  Arch Oral Biol 19:733-739, 1974.
  • Cox MO, Crawford JJ, Lundblad RL, McFall WT:  Oral Leukocytes and Gingivitis in the Primary Dentition.  J Perio Res 9:23-28, 1974.
  • Blatt PM, Lundblad RL, Kingdon HS, McClean G, Roberts HS:  Thrombogenic Materials in Prothrombin Complex Concentrates.  Annals Int Med 34:766-770, 1974.
  • Kingdon HS, Lundblad RL:  Factors Affecting the Evolution of Factor XIa During Blood Coagulation. J Lab Clin Med 85:826-831, 1975.
  • Lundblad RL:  The Reaction of Bovine Thrombin with N-Butyrylimidazole Two Different Reactions Resulting in the Inhibition of Catalytic Activity.  Biochemistry 14:1033-1037, 1975.
  • Kingdon HS, Lundblad RL:  Biochemistry of Factor IX.  The Handbook of Hemophilia, ed. KM Brinkhous and HC Hempker, Excerpta Medica, 107-118, 1975.
  • Kingdon HS, Lundblad RL, Veltkamp J, Aronson DL:  Potentially Thrombogenic Materials in Factor IX Concentrates.  Thromb Diath Haemorrh (Stuttg), 33:617-631, 1975.
  • Lundblad RL, Uhteg LC, Vogel CN, Kingdon HS, Mann KG:  Preparation and Partial Characterization of Two Forms of Bovine Thrombin.  Biochem Biophys Res Commun 66:482-489, 1975.
  • Lundblad RL, White GC, Webster WP, Kingdon HS:  The Hemostatic Mechanism:  Mechanistic, Diagnostic and Therapeutic Considerations.  North Carolina State Dental Journal, No. 3:18-21, 1975.
  • Koehler KA, Gabriel DA, Hiskey RG, Lundblad RL, Roberts HR, Nelsestuen GL:  Prothrombin's Calcium Ion Binding Site.  Carbon-13 Nuclear Magnetic Resonance Studies.  Thromb Res 7:871-877, 1975.
  • Mohammed SF, Whitworth C, Chuang HYK, Lundblad RL, Mason RG:  Multiple Active Forms of Thrombin:  Binding to Platelets and Effects on Platelet Function.  Proc Nat Acad Sci (USA) 73:1660-1663, 1976.
  • Myrmel KH, Lundblad RL, Mann KG:  Characteristics of The Association Between Prothrombin Fragment 2 and a-Thrombin.  Biochemistry 5:1767-1773, 1976.
  • Vogel, CN, Butkowski RJ, Mann KG, Lundblad RL:  The Effect of Polylysine on The Activation of Prothrombin. Polylysine Replaces Calcium Ions and Factor V in the Factor Xa-Catalyzed Activation of Prothrombin.  Biochemistry 15:3265-3269, 1976.
  • Raulais D, Hageman J, Ontjes DA, Lundblad RL, Kingdon HS:  The Complete Amino Acid Sequence of Rat Thyrocalcitonin.  Europ J Biochem 64:607-611, 1976.
  • Lundblad RL, Kingdon HS, Mann KG:  Thrombin.  Methods in Enzymol. Vol. 45 (ed. L Lorand), 156-176, 1976.
  • Workman EF Jr, White GC, Lundblad RL:  Platelet-Thrombin Interactions as Assessed by Affinity Chromatography.  Thromb Res 9:491-503, 1976.
  • White GC, Roberts HR, Kingdon HS, Lundblad RL:  Prothrombin Complex Concentrates.  Potentially Thrombogenic Materials and Clues to the Mechanism of In Vivo Thrombosis.  Blood 49:159-170, 1977.
  • Uhteg LC, Lundblad RL:  The Modification of Tryptophan in Bovine Thrombin.  Biochim Biophys Acta 491:551-557, 1977.
  • Workman EF, White GC II, Lundblad RL:  High Affinity Binding of Thrombin to Platelets.  Inhibition by Tetranitromethane and Heparin.  Biochem Biophys Res Commun 75:925-932, 1977.
  • Lundblad RL, Hoffman S, Noyes CM, Kingdon HS:  Purification and Partial Characterization of Deoxyribonuclease I from Bovine Parotid Gland.  J Dent Res 56:320-326, 1977.
  • Workman EF Jr, Lundblad RL:  The Hepatic Synthesis of the Non-Vitamin K-Dependent Coagulation Factors.  Seminars in Thrombosis and Hemostasis 4:15-28, 1977.
  • Lundblad RL, Fenton JW II, Mann KG eds.:  Chemistry and Biology of Thrombin, Ann Arbor Science Publishers, Inc., Ann Arbor Michigan, 560 pp., 1977.
  • Workman EF Jr, Uhteg LC, Kingdon HS, Lundblad RL:  Isolation and Characterization of Bovine Thrombin, in Chemistry and Biology of Thrombin, Ann Arbor Science, pp. 23-42, 1977.
  • Kingdon HS, Noyes CM, Lundblad RL:  Some Aspects of the Primary Structure of Bovine Alpha, Beta and Gamma Thrombins, in Chemistry and Biology of Thrombin, Ann Arbor Science, pp. 91-96, 1977.
  • White GC II, Workman EF Jr, Lundblad RL:  Platelet-Thrombin Interactions, The Platelet as a Substrate for Thrombin, in Chemistry and Biology of Thrombin, Ann Arbor Science, pp. 479-498, 1977.
  • Workman EF Jr, White GC II, Lundblad RL:  Chemical Modification of Thrombin:  Effect on Binding to Platelets, in Chemistry and Biology of Thrombin, Ann Arbor Science, pp. 499-506, 1977.
  • Workman EF Jr, White GC II, Lundblad RL:  Structure-Function Relationships in the Interaction of a-Thrombin with Blood Platelets.  J Biol Chem 252:7118-7123, 1977.
  • White GC II, Workman EF Jr, Lundblad RL:  The Binding of Thrombin to Thrombasthenic Platelets.  J Lab Clin Med 91:76-82, 1978.
  • Workman EF Jr, Lundblad RL:  The Effect of Monovalent Cations on the Catalytic Activity of Thrombin. Arch Biochem Biophys 185:544-548, 1978.
  • Workman EF Jr, Lundblad RL:  On the Preparation of Bovine a-Thrombin.  Thromb Haemos 39:193-200, 1978.
  • Griffith MJ, Kingdon HS, Lundblad RL:  Fractionation of Heparin by Affinity Chromatography on Covalently-Bound Human a-Thrombin.  Biochem Biophys Res Commun 83:1198-1205, 1978.
  • Leeb JI, Featherstone GL, Lundblad RL:  The Effect of Ethionine Intoxication on the Membrane Proteins of Rat Parotid Gland Secretory Granules.  Biochem Biophys Res Commun 83:1474-1478, 1978.
  • White GC II, Workman EF Jr, Holahan JR, Lundblad RL:  Alterations in Platelet Membrane Structure and Function During Storage at Ambient Temperature, in The Blood Platelet in Transfusion Therapy, eds. G.A. Jamieson and T.J. Greenwalt, Alan R. Liss, Inc., New York, New York pp. 113-118, 1978.
  • Vogel CN, Kingdon HS, Lundblad RL:  Correlation of In Vivo and In Vitro Inhibition of Thrombin by Plasma Inhibitors.  J Lab Clin Med 93:661-673, 1979.
  • Griffith MJ, Kingdon HS, Lundblad RL:  Inhibition of the Heparin-Antithrombin III/Thrombin Reaction by Active Site Blocked-Thrombin.  Biochem Biophys Res Comm 87:686-692, 1979.
  • Griffith MJ, Kingdon HS, Lundblad RL:  The Interaction of Heparin with Human a-Thrombin.  Effect on The Hydrolysis of Anilide Tripeptide Substrates.  Arch Biochem Biophys 195:378-384, 1979.
  • White GC II, Workman EF Jr, Lundblad RL:  The Effect of Ambient Storage on Platelet Membrane Structure and Response to Thrombin.  Transfusion 19:411-419, 1979.
  • Lundblad RL, Noyes CM, Mann KG, Kingdon HS:  The Covalent Differences Between Bovine a- and b-Thrombin.  A Structural Explanation for the Changes in Catalytic Activity.  J Biol Chem 254:8524-8528, 1979.
  • White GC II, Kingdon HS, Lundblad RL:  Prothrombin Complex Concentrates.  Current Topics in Hematology 2:203-244, 1979.
  • Griffith MJ, Beavers G, Kingdon HS, Lundblad RL:  Effect of Monovalent Cations on the Heparin-Enhanced Antithrombin III/Thrombin Reaction.  Thromb Res 17:29-39, 1980.
  • Griffith MJ, Kingdon HS, Lundblad RL:  Hydrolysis of N-a-Benzoyl-L-Phenylalanyl-L-Valyl-N-Arginine-p-nitroanilide by Human Alpha-Thrombin in the Presence of Heparin.  Thromb Res 17:83-90, 1980.
  •  Kingdon HS, White GC II, Blatt PM, Roberts HR, Lundblad RL:  Vitro and In Vivo Assays of Thrombogenic Enzymes in Prothrombin Complex Concentrates, and Correlation of These Assays with Clinical Thrombotic Disease, in Reviews of Hematology (ed. JL Ambrus), PJD Publications, Ltd., Westbury, N.Y., Volume 1, pp. 229-245, 1980.
  • Lundblad RL, Nissen LW, Roberts HR, White GC II, Blatt PM, Kingdon HS:  Factors Affecting the Thrombogenic Properties of Prothrombin Complex Concentrates, in Reviews of Hematology (ed. JL Ambrus), PJD Publications, Ltd., Westbury, N.Y., Volume 1, pp. 247-266, 1980.
  • Lundblad RL, Workman EF JR:  Thrombin, CRC Handbook on Clinical Science, Section I, Hematology, Vol. 3, 149-169, 1980.
  • Lundblad RL, Brown WV, Mann KG, Roberts HR (editors):  The Chemistry and Biology of Heparin, Elsevier North Holland, 566 pages, 1980.
  • Griffith MJ, Lundblad RL:  Dissociation of Antithrombin III-Thrombin Complex.  Formation of Active and Inactive Antithrombin III.  Biochemistry 20:105-110, 1981.
  • White GC II, Lundblad RL, Griffith MJ:  Structure-Function Relationships in Platelet-Thrombin Reactions.  Inhibition of Platelet-Thrombin Reaction by Lysine Modification.  J Biol Chem 256:1763-1766, 1981.
  •   Lundblad RL, White GC II, Roberts HS, Kingdon HS:  Biochemical Considerations Regarding the Thrombogenicity of Prothrombin Complex Concentrates.  in Perspectives in Hemostasis (ed. J Fareed, HL Messmore, JW Fenton, II and KM Brinkhous), Pregammon Press, Elmsford, New York, pp. 281-289, 1981.
  • Lundblad, RL, Roberts, JC, Johnston, DK, Featherstone, GL. Griffith, MJ., Acceleration by Calcium of the inactivation of Thrombin by Plasma Proeinase Inhibitors, Thromb.Res. 22, 135-146, 1981.
  • Braunstein KM, Noyes CM, Griffith MJ, Lundblad RL, Roberts HR:  Characterization of the  Defect in Factor  IX Chapel Hill  Activation  by Factor XIa. J. Clin. Invest. 68:1420-1426, 1981.
  • Roberts HR, Griffith MJ, Braunstein KM, Lundblad RL:  Structural Abnormalities of the Vitamin K-Dependent Clotting Factors.  in Hemophilia and Hemostasis, Alan R. Liss, New York, New York, pp. 85-102, 1981.
  • Mann KG, Lundblad RL:  Biochemistry of Thrombin.  in Textbook of Hemostasis and Thrombosis (ed. RW Colman, J Hirsh, VJ Marder and EW Salzman), J.B. Lippincott, Philadelphia, Pennsylvania, pp. 112-126, 1981.
  • Lundblad RL, Roberts HR:  The Acceleration by Polylysine of the Activation of Factor X by Factor IXa.  Thromb Res 25:319-329, 1982.
  • Tarvers RC, Noyes CM, Roberts HR, Lundblad RL:  Influence of Metal Ions on Prothrombin Self-Association.  Demonstration of Dimer Formation by Intermolecular Cross-Linking with Dithiobis- (succinimidylpropionate).  J Biol Chem 257:10708-10714, 1982.
  • Griffith MJ, Reisner HM, Lundblad RL:  Measurement of Human Factor IXa Activity in an Isolated Factor X Activation System.  Thromb Res 22:289-302, 1982.
  • Noyes CM, Griffith MJ, Roberts HR, Lundblad RL:  Identification of the Molecular Defect in Factor IXChapel Hill.  Substitution of Histidine for Arginine at Position 145.  Proc Nat Acad Sci USA, 80:4200-4202, 1983.
  • Lundblad RL, Noyes CM:  Observations on the Reaction of 2-Hydroxy-5-Nitrobenzyl Bromide with a Peptide-Bound Tryptophanyl Residue.  Analyt Biochem 136:93-100, 1984.
  • Tarvers RC, Roberts HR, Lundblad RL:  Self Association of Bovine Prothrombin Fragment 1 in the Presence of Metal Ions.  Use of a Covalent Crosslinking Reagent to Study the Reaction.  J Biol Chem 259:1944-1950, 1984.
  • Lundblad RL, Noyes CM:   Chemical Reagents for the Modification of Proteins.  CRC Press, Boca Raton, Florida, Volume I, 170 pp.; Volume II, 169 pps., 1984.
  • Lundblad RL, Nesheim ME, Straight DL, Sailor S, Bowie J, Jenzano J, Roberts DJ, Mann KG:  Bovine a- and b-Thrombin.  Changes in Reactivity at the Active Site are Responsible for Reduced Fibrinogen Clotting Activity of b-Thrombin.  J Biol Chem 259:6991-6995, 1984.
  • Lundblad RL, Jenzano JW, Straight DL, White GC II:  Thrombin:  Specific Chemical Modification, in The Thrombin(ed. R Machovich), CRC Press, Boca Raton, Florida, Volume I, pp. 23-33, 1984.
  • White GC II, Knupp CL, Lundblad RL:  The Interaction of Thrombin with Platelets.  in The Thrombin(ed. R. Machovich), CRC Press, Boca Raton, Florida, Volume II, pp. 25-41, 1984.
  •  Monroe DM, Noyes CM, Lundblad RL, Kingdon HS, Griffith MJ:  Interaction of Substrates with Glutamine Synthetase After Limited Proteolysis.  Biochemistry 23:4565-4572, 1984.
  • Lundblad RL, Jenzano JW:  Effect of Monovalent Cations on Bovine  a- and b-Thrombin:  Importance of Substrate Structure.  Thromb Res 37:53-59, 1985.
  • Griffith MJ, Breitkrevtz L, Trapp H, Briet E, Noyes CM, Lundblad RL, Roberts HR:  Characterization of the Clotting Activities of Structurally Different Forms of Activated Factor IX.  Enzymatic Properties of Normal Human Factor Ixa , Factor Ixa , and Activated Factor IXCHAPEL HILL. J Clin Invest 75:4-10, 1985.
  • Church FC, Lundblad RL, Noyes CM:  Modification of Histidines in Human Prothrombin, Effect of the Interaction of Fibrinogen with Thrombin from Diethyl Pyrocarbonate-Modified Prothrombin.  J Biol Chem 260:4936-4940, 1985.
  • Church FC, Lundblad RL, Noyes CM, Tarvers RC:  Effect of Divalent Cations on the Limited Proteolysis of Prothrombin by Thrombin.  Arch Biochem Biophys 240:607-612, 1985.
  • McGraw RA, Davis LM, Noyes CM, Lundblad RL, Roberts HR, Graham JB, Stafford DW:  Evidence for a Prevalent Dimorphism in the Activation Peptide of Human Coagulation Factor IX.  Proc Nat Acad Sci USA 82:2847-2851, 1985.
  • Monroe DM, Noyes CM, Griffith MJ, Lundblad RL, Kingdon HS:  Structure and Enzymatic Properties of Escherichia coli Glutamine Synthetase Subjected to Limited Proteolysis.  in Current Topics in Cellular Regulation, Volume 27 (Modulation by Covalent Modification) Academic Press, Orlando, Florida, pp 361-372, 1985.
  •  Jenzano JW, Courts NF, Timko DA, Lundblad RL:  Levels of Glandular Kallikrein in Whole Saliva Obtained from Patients with Solid Tumors Remote from the Oral Cavity.  J Dent Res 65:67-70, 1986.
  • Tarvers RC, Noyes CM, Tarvers JK, Lundblad RL:  Mechanism of the Calcium Dependent Self-Association of Bovine Prothrombin.  Use of a Covalent Crosslinking Reagent to Study the Reaction. J Biol Chem 261:4855-4859, 1986.
  • Jenzano JW, Hogan SL, Lundblad RL:  Factors Influencing Measurement of Human Salivary Lysozyme.  J Clin Microbiol 24:963-967, 1986.
  • Jenzano JW, Hogan SL, Noyes CM, Featherstone GL, Lundblad RL:  Comparison of Five Techniques for the Determination of Protein Content in Mixed Human Saliva.  Anal Biochem 159:370-376, 1986.
  • Tarvers RC, Roberts HR, Straight DL, Featherstone GL, Lundblad RL:  Homo and Heterodimer with Prothrombin and Prothrombin Fragment 1 in the Presence of Calcium Ions.  Archs Biochem Biophys, 257:439-443, 1987.
  • Mann KG, Lundblad RL:  Biochemistry of Thrombin in Textbook of Hemostasis and Thrombosis, 2nd Ed. (ed. RW Colman, J Hirsh, VJ Marder and ED Salzman), J.B. Lippincott, Philadelphia, Pennsylvania, pp. 148-160, 1987.
  • Lundblad RL, Jenzano JW, Robert HR:  Interaction of Polylysine with Bovine Factor Xa.  Thombosis Res, 48:395-402,, 1987.
  • Jenzano, JW, Lundblad, RL: Effect of Amines and Polyamines on the Turbidimetric and Lysoplate Assays for Lysozyme. J. Clin. Microbiol, 26:34-37, 1988.
  • Lundblad, RL, Noyes, CM, Featherstone, GL, Harrison, JH,  Jenzano, JW: The Reaction of Bovine Alpha-Thrombin with  Tetranitromethane.  Characterization of the Modified Protein. J Biol Chem, 263:3729-3734, 1988.
  •  Manly DT, Featherstone GL, Roberts HR, Jenzano JW, Lundblad RL:  Influence of Monovalent and Divalent Cations on Some Active Site Properties of Human Factor Xa.  Thrombosis Research 49:343-  351,  1988.
  • Jenzano, JW, Coffey, JC, Heizer, WD, Lundblad, RL Scili, AG: The Assay of Glandular Kallikrein and Prekallikrein in Human Mixed Saliva, Archives of Oral Biology 33:641-644, 1988.
  •  Lundblad, RL: A hydrophobic Site in Human Prothrombin Present in a Calcium-Stabilized Conformer,  Biochemical and  Biophysical Research Communications 157:295-300, 1988.
  •  Monroe, DM., McCord, DM., Huang, M.-N., High, KA., Lundblad, RL, Kasper, CK., and Roberts,     HR: Functional  Consequences of an Arginine180 to Glutamine Mutation in  Factor IX Hilo. Blood       73:1540-1544, 1989.
  • Lundblad, RL; Site-Specific Chemical Modification of  Proteins:  Application to the Study of theBiological Functions of Thrombin, Proceedings of the First Brazilian Conference on Proteins,             UNICAMP, Brazil, 1990.
  •   Lundblad, RL: Chemical Reagents for Protein Modification,  2nd Edition, CRC Press, Boca Raton,FL., 346 pps, 1991.
  • Venezie, RD., Jenzano, JW., and Lundblad, RL:  Differentiation of  Myeloperoxoidase and Glandular Peroxidase in Biological Fluids: Application to Human Saliva. J. Clin.  Lab. Analysis. 5:57-59, 1991.
  •   Cohen, WM., Wu, H.-f., Featherstone, GL., Jenzano, JW. and Lundblad, RL: Linkage between Blood Coagulation and Inflammation: Stimulation of Neutrophil Tissue Kallikrein by Thrombin.         Biochem. Biophys. Res. Commun. 178:315-320, 1991
  •   Jenzano, JW, Hogan, SL., and Lundblad, RL:  Effect of  Age, Sex and Race on the Level of Glandular Kallikrein in Human Mixed Saliva, Agents and Actions 35:29-33, 1992.
  •   Wu, H.-f, White, GC,II., Workman, EF., Jr., Jenzano,  JW., and Lundblad, RL: Interaction of  Immobilized Thrombin with Platelets: Retention of Catalytic Activity by  Bound Thrombin.                 Thrombosis Research 67:419-427, 1992.
  •   Jenzano, JW., Su, H.-w., Featherstone, GL. and Lundblad,  RL: Molecular Diversity of TissueKallikrein in Human Saliva, Recent Progress in Kinins(Agents and Actions Suppl  38), 137-143,        1992.
  • Davenport, JB., Pucilowska, JB., Clemmons, DR., Lundblad, R., Spenser, JA. and Underwood, LE:Tissue-specific  Expression of Insulin-Like Growth Factor Binding Protein-3 Protease Activity        during Rat Pregnancy. Endocrinology 103:2505-2512, 1992.
  • Gomperts, E., Lundblad, R. and Adamson, R.: The Manufacturing  Process of Recombinant FactorVIII, Recombinate, Transfusion Medicine Reviews 6:247-251, 1992.
  • Jenzano, JW, Featherstone, GL, and Lundblad, RL: Factors in Biological Fluids Affect Gel Filtration Behavior of Epidermal Growth Factor. Peptide Research 5:255-257,  1992.
  • Wu, H-.f., Venezie, RD, Cohen, WM., Jenzano, JW and Lundblad, RL: Identification of Tissue Kallikrein Messenger RNA in Neutrophils with the Polymerase Chain Reaction, Agents and Action,      38:27-30, 1993.
  • Lundblad, RL., Tsai, J., Wu, H.-f., Jenzano, JW, White, GC,II and Connolly, TM:  Hydrophobic  Affinity  Chromatography of Human Thrombin, Archives of Biochemistry  and Biophysics 110:109-     112, 1993.
  • Wu, H.-f., Xu, L.-h., Jenzano, JW., Rinehart, CA.,  Kaufmann, DG. and Lundblad, RL:  Expression  of Tissue  Kallikrein in Normal and Transfected Human Endometrial  Stromal Cells, Pathobiology  61:123-127, 1993.
  • Taiariol, V., Oakley, R., Maciukas, S., Kingdon, H. and  Lundblad, R.: A Comparative Study on the Growth of a Transfectoma Cell Line Secreting Antibody Against Core-LPS in the Hollow Fiber Bioreactor, The Packed Bed Bioreactor and the Stirred Tank Bioreactor, The Baxter Technical Journal, Quarter 3, 1993.
  • Lundblad, RL:  Techniques in Protein Modification, CRC Press, Boca Raton, FL, 288 pps, 1994.
  • Wu, H.-f., Lundblad, RL. and Church, FC:  Neutralization of Heparin by Neutrophil Lactoferrin, Blood 85:421-428, 1995.
  • Lundblad, RL:  Chemical Modification, in Protein Labfax,  ed. P.Engel, Bios Scientific Publishers, Oxford, pps. 287-298, 1996.
  • Kumar, HR., Hague, C., Haley, T., Starr, CM. Besman, M.  Lundblad, R. and Baker, D: Elucidation of the N-linked Oligosaccharide Structures of Recombinant Human Factor VIII Using  Fluorophore Assisted Electrophoresis, Biotechnology and Applied  Biochemistry, 24:207-216, 1996.
  • Lundblad, RL. and Bradshaw, RA:  Applications of site-specific chemical modification in the manufacture of  biopharmaceuticals: I. an overview. Biotechnology and Applied  Biochemistry 26,          143-151. 1997.
  •  Lundblad, RL., Bergstrom, J., De Vreker, R., Bray, G., Gomperts, E., Baker, D., Kingdon, HS., Mann, KG., Hartshrorn, J. and Jenny, RJ:  Measurement of Active Coagulation Factors in     Autoplex®-T with Colorimetric Active Site-Specific Assay Technology. Thrombosis and  Haemostasis  80, 811-815, 1998. 
  • Sapan, CV., Lundblad, RL. and Price, NC. Colorimetric protein  assay techniques. Biotechnology and Applied Biochemistry 29, 99-108, 1999.
  • Lundblad, RL,  Kingdon, HS, Mann, KG, and White, GW, Issues with the assay of Factor VIII Activity in Plasma and Factor VIII Concentrates.  Thrombosis and Haemostasis 84, 942-948, 2001.
  • Lundblad, RL, Approach to assay validation in the development of biopharmaceuticals.  Biotechnology and Applied Biochemistry 34, 195-197, 2001.
  • Kingdon, HS and Lundblad, RL  An adventure in biotechnology: The development of  Haemophilia A  therapeutics: From whole blood transfusion to recombinant DNA to gene therapy.  Biotechnology and Applied Biochemistry 35, 141-148, 2002.
  • Jenny, RS, Mann, KG, and Lundblad, RL, A critical review of methods for the cleavage of fusion proteins, Protein Expression and Purification 31, 1-11, 2003.
  • Lundblad, RL and Price, NC, Determination of protein concentration in the manufacture and characterization of biopharmaceuticals with a note on validation process, Bioprocess International,             January 2004, 1-7, 2004.
  • Lundblad, R.L., Bradshaw, R.A., Gabriel, D., Ortel, T.L., Lawson, J., and Mann, K.G., A review ofthe therapeutic uses of thrombin, Thrombosis and Haemostasis 91, 851-860, 2004.
  • Lundblad, R.L. and Wagner, P.M., Some Rumination on the Issue of Assay Validation forBiopharmaceuticals, PreclinicaJuly/August, 2004, 1-4, 2004.
  • Lundblad, R.L., Chemical Reagents for Protein Modification,  3rd Edition, CRC Press, Boca Raton, Florida,  November, 2004.
  • Lundblad, R.L. and Wagner, P.M., Fact and Fantasy in the Use of Proteomics in the Development of  Fact and Fantasy in the Use of Proteomics in the Development of Diagnostics.  Is the technology necessary or even useful in the discovery of new biomarkers?, IVD Technology, March, 2005.
  • Lundblad, R.L., The Evolution of Protein Chemistry to Proteomics: Basic Science to Clinical   Application, CRC Press (Taylor and Francis), Boca Raton, Florida, 2005.
  • Lundblad, R.L. and White, G.C., II., The Interaction of Thrombin with Blood Platelets, Platelets, 16, 373-385, 2005.  
  • Lundblad, R.L, Lundblad, G.T., and Burgess, C., Accelerating Biopharmaceutical Product  Development.  Part 1.  Importance of Front-Loading the Product Development Process and the “Fuzzy Front End.”  Bioprocess International, March, 2006
  • Lundblad, R.L., Lundblad, G.T., and Burgess, C., Accelerating Biopharmaceutical Product Development – Information Resources at the Fuzzy Front End, Bioprocess International, April, 2006.
  • Sapan, C.V. and Lundblad, R.L., Considerations Regarding the Use of Blood Samples in the Proteomic Identification of Biomarkers for Cancer Diagnosis, Cancer Genomics and Proteomics, 33,          227-231, 2006.
  • Lundblad, R.L. and Bradshaw, R.A., Addressing Product Improvement Using Chemical Modification  in Biopharmaceutical Manufacture.  A case study in blood coagulation factor VIII,                 Bioprocess International, September 2006.
  • Jenny, N.S., Lundblad, R.L., and Mann, K.G., Thrombin, in Hemostasis and Thrombosis.  Basic Principles and Clinical Practice, 5th edn., ed. R.W. Colman, V.J. Marder, A.W. Cloves, J.N. George and S.Z. Goldhaber, Lippincott, William & Wilkins, Philadelphia, PA,  Chapter 10, pps 193-213. 2007.
  • Lundblad, R.L., Is the Power of Monoclonal less than One?, Bioprocess International, October,  2006.
  • Sapan, C.V., Reisner, H.M., and Lundblad, R.L., Antibody Therapy (IVIG): Evaluation of the use genomics and proteomics for the study of immunomodulation therapeutics, Vox Sanguinis,  92, 197-205,  2007.
  • Burgess, C. and Lundblad, R.L., Plasma or serum in proteomic analysis, Clinical Laboratory  International, 31(1), 10-11, 2007.
  • Lundblad, R.L. and Wagner, P.M., Old Wine in New Bottles.  Interpreting the relationship between proteomics and biomarkers, IVD Technology 13(3), 74, April, 2007.
  • Lundblad, R.L. and Wagner, P.M. Acronyms and other neologisms in biomedical research, Bioprocess International  5, 16-18, 2007.
  • Lundblad, R.L., Compendium for Biochemistry and Molecular Biology, Taylor & Francis,  Boca Raton, Florida, June, 2007.
  • Lundblad, R.L., Throwing the flag on biosimilars, Bioprocess International, March, 2008.
  • Lundblad, R.L., Assessing the progress (or lack thereof) in biomarkers, IVD Technology, January, 2009.
  • Reisner, H.M. and Lundblad, R.L., Identifying residues in antigenic determinants by chemical modification, in Epitope Mapping Protocols, 2nd edn., ed U.Reincke and M Schutkowski, Humana           Press, Totowa, NJ, USA, May, 2009.
  • Lundblad, R.L, Application of Solution Protein Chemistry to Biotechnology, Taylor & Francis, Boca Raton, Florida, May, 2009.
  • Lundblad, R.L., Approaches to the Conformational Analysis of Biopharmaceuticals, Taylor & Francis,  Boca Raton,  Florida, December, 2009.
  • Lundblad, R.L., In Vitro Assays for Therapeutic Enzyme Characterization, Bioprocess International, January , 2010.
  • Lundblad, R.L., Handbook of Biochemistry and Molecular Biology, 4nd edition, Taylor  &  Francis, Boca Raton, Florida,  June, 2010.
  • Lundblad, R.L., The Development and Application of Biomarkers, Taylor & Francis, Boca Raton, Florida, January  2011.
  • Lundblad, R.L., The Chemical Modification of Biological Polymers, Taylor & Francis, Boca Raton, Florida, September, 2011.
  • Lundblad, R.L., The Biotechnology of Plasma Proteins, Taylor & Francis, Boca Raton, Florida, September, 2012.
  • Lundblad, R.L., Chemical Reagents for Protein Modification, 4th edition, Taylor & Francis, Boca Raton, Florida, July, 2014.
  • Sapan, C.V. and Lundblad, R.L., Review of Methods for Determination of Total Protein and Peptide Concentration in Biological Samples, Clin.Proteomics, 9, 268-276, 2015.
  • Lundblad, R.L., Drug Design, in Encyclopedia of Cell Biology, Vol. 1., ed. R.A. Bradshaw and P.Stahl, pps. 135-140, Academic Press, Waltham, MA, 2016.
  • Lundblad, R.L., Chemical Biology, in Encyclopedia of Cell Biology, Vol. 1., ed. R.A. Bradshaw and P.Stahl,  pps. 128-134, Academic Press, Waltham, MA., 2016.
  • Datto, M. and Lundblad, R.L., Chemical Modification of Nucleic Acids and Next Gen Sequencing, , in Encyclopedia of Cell Biology, Vol. 1., ed. R.A. Bradshaw and P.Stahl, pps. 24-35, Academic Press, Waltham,MA,  2016.
  • Bradshaw, R.A. and Lundblad, R.L., Kallikrein, , in Encyclopedia of Cell Biology,Vol 1., ed. R.A. Bradshaw and P.Stahl, pps. 699-705. Academic Press, Waltham, MA, 2016.
  • de Ridder, G.G., Lundblad, R.L., and Pizzo, S.V., Actions of thrombin in the interstitium, Journal of Thrombosis and Haemostasis, 14, 40-47, 2016.
  • Pizzo, S.V., Lundblad, R.L., and Willis, M.S., Proteolysis in the Interstitial Space, CRC Press, expected, July, 2016


 PATENTS

  • U.S. Patent # 5,354,682. "Viral-Safe Purified Human Thrombin"
  • U.S. Patent # 5,576,291. "Activated Factor VIII as a Therapeutic Agent and Method of Treating Factor VIII Deficiency"
  • U.S. Patent #6,268,200.  "Biotherapeutic Virus Attenuation Using Variable Frequency Microwave