Biomarker Discovery and Evaluation

I recently came across an excellent article on the discovery and evaluation of biomarkers while search for something else.

Marshall, R.P., Simpson, J.K., and Lukey, P.T., Strategies for biomarker discovery in fibrotic disease, Biochim.Biophys.Acta 1832, 1079-1087, 2014.

In the current world of targeted searches the value of serendipity is mostly ignored.