ROGER LAUREN LUNDBLAD

                                                                      PUBLICATIONS (2000-Present)

Lundblad, RL,  Kingdon, HS, Mann, KG, and White, GW, Issues with the assay of Factor VIII Activity in Plasma and Factor VIII Concentrates.  Thrombosis and Haemostasis 84, 942-948, 2001.

Lundblad, RL, Approach to assay validation in the development of biopharmaceuticals. Biotechnology and Applied Biochemistry 34, 195-197, 2001.

Kingdon, HS and Lundblad, RL  An adventure in biotechnology: The development of  Haemophilia A therapeutics: From whole blood transfusion to recombinant DNA to gene therapy.  Biotechnology and Applied Biochemistry 35, 141-148, 2002

Jenny, RS, Mann, KG, and Lundblad, RL, A critical review of methods for the cleavage of fusion  proteins, Protein Expression and Purification 31, 1-11, 2003.

 Lundblad, RL and Price, NC, Determination of protein concentration in the manufacture and characterization of biopharmaceuticals with a note on validation process, Bioprocess InternationalJanuary 2004, 1-7, 2004.

Lundblad, R.L., Bradshaw, R.A., Gabriel, D., Ortel, T.L., Lawson, J., and Mann, K.G., A review of  the therapeutic uses of thrombin, Thrombosis and Haemostasis 91, 851-860, 2004.

Lundblad, R.L. and Wagner, P.M., Some Rumination on the Issue of Assay Validation for Biopharmaceuticals, PreclinicaJuly/August, 2004, 1-4, 2004

Lundblad, R.L., Chemical Reagents for Protein Modification,  3rd Edition, CRC Press, Boca Raton, Florida,  November, 2004

Lundblad, R.L. and Wagner, P.M., Fact and Fantasy in the Use of Proteomics in the Development of Fact and Fantasy in the Use of Proteomics in the Development of Diagnostics.  Is the technology necessary or even useful in the discovery of new biomarkers?, IVD Technology, March, 2005.

Lundblad, R.L., The Evolution of Protein Chemistry to Proteomics: Basic Science to Clinical Application, CRC Press (Taylor and Francis), Boca Raton, Florida, 2005.

Lundblad, R.L. and White, G.C., II., The Interaction of Thrombin with Blood Platelets, Platelets, 16, 373-385, 2005.

Lundblad, R.L, Lundblad, G.T., and Burgess, C., Accelerating Biopharmaceutical Product  Development.  Part 1.  Importance of Front-Loading the Product Development Process and the “Fuzzy Front End.”  Bioprocess International, March, 2006 

Lundblad, R.L., Lundblad, G.T., and Burgess, C., Accelerating Biopharmaceutical Product Development – Information Resources at the Fuzzy Front End, Bioprocess International, April, 2006.

 Sapan, C.V. and Lundblad, R.L., Considerations Regarding the Use of Blood Samples in the Proteomic Identification of Biomarkers for Cancer Diagnosis, Cancer Genomics and Proteomics, 33, 227-231, 2006.

Lundblad, R.L. and Bradshaw, R.A., Addressing Product Improvement Using Chemical  Modification  in Biopharmaceutical Manufacture.  A case study in blood coagulation factor VIII,  Bioprocess International, September 2006.

Jenny, N.S., Lundblad, R.L., and Mann, K.G., Thrombin, in Hemostasis and Thrombosis.  Basic Principles and Clinical Practice, 5th edn., ed. R.W. Colman, V.J. Marder, A.W. Cloves, J.N. George And S.Z. Goldhaber, Lippincott, William & Wilkins, Philadelphia, PA,  Chapter 10, pps 193-213, 2007 

Lundblad, R.L., Is the Power of Monoclonal less than One?, Bioprocess International, October,  2006

Sapan, C.V., Reisner, H.M., and Lundblad, R.L., Antibody Therapy (IVIG): Evaluation of the use genomics and proteomics for the study of immunomodulation therapeutics, Vox Sanguinis92, 197-205,  2007.

Burgess, C. and Lundblad, R.L., Plasma or serum in proteomic analysis, Clinical Laboratory International, 31(1), 10-11, 2007

Lundblad, R.L. and Wagner, P.M., Old Wine in New Bottles.  Interpreting the relationship between proteomics and biomarkers, IVD Technology 13(3), 74, April, 2007

Lundblad, R.L. and Wagner, P.M. Acronyms and other neologisms in biomedical research, Bioprocess International  5, 16-18, 2007      

Lundblad, R.L., Compendium for Biochemistry and Molecular Biology, Taylor & Francis, Boca Raton, Florida,  June, 2007.

Lundblad, R.L., Throwing the flag on biosimilars, Bioprocess International, March, 2008

Lundblad, R.L., Assessing the progress (or lack thereof) in biomarkers, IVD Technology, January 2009

 Reisner, H.M. and Lundblad, R.L., Identifying residues in antigenic determinants by chemical  modification, in Epitope Mapping Protocols, 2nd edn., ed U.Reincke and M Schutkowski, Humana        Press, Totowa, NJ, USA, May, 2009

 Lundblad, R.L, Application of Solution Protein Chemistry to Biotechnology, Taylor & Francis, Boca Raton, Florida, May, 2009

Lundblad, R.L., Conformational Analysis Methods for Biotechnology Products, Taylor & Francis,  Boca Raton,  Florida, , December, 2009

 Lundblad, R.L. and MacDonald, F., Handbook of Biochemistry and Molecular Biology, 4th Edition,Taylor & Francis, Boca Raton, Florida, June, 2010

Lundblad, R.L., Development Application of Biomarkers, Francis & Taylor, Boca Raton, Florida, January, 2011

Lundblad, R.L, The Chemical Modification of Biological Polymers, Taylor & Francis, Boca Raton, Florida, Sepember 2011

Lundblad, R. L., The Biotechnology of Plasma Proteins, Taylor and Francis, September, 2012

Lundblad, R.L., Chemical Reagents for Protein Modification, 4th edition, Taylor and Francis, May, 2014

Sapan, C.V. and Lundblad, L.L., Review of Methods for Determination of Protein Concentration and Peptide Concentration in Biological Samples, Clinical Proteomics 9, 268-276, 2015

Lundblad, R.L., Drug Design, in Encyclopedia of Cell Biology, Vol. 1., ed. R.A. Bradshaw and P.Stahl, pps. 135-140, Academic Press, Waltham, MA, 2016.

Lundblad, R.L., Chemical Biology, in Encyclopedia of Cell Biology, Vol. 1., ed. R.A. Bradshaw and P.Stahl,  pps. 128-134, Academic Press, Waltham, MA., 2016.

Datto, M. and Lundblad, R.L., Chemical Modification of Nucleic Acids and Next Gen Sequencing, , in Encyclopedia of Cell Biology, Vol. 1., ed. R.A. Bradshaw and P.Stahl, pps. 24-35, Academic Press, Waltham,MA,  2016.

Bradshaw, R.A. and Lundblad, R.L., Kallikrein, , in Encyclopedia of Cell Biology,Vol 1., ed. R.A. Bradshaw and P.Stahl, pps. 699-705. Academic Press, Waltham, MA, 2016.

de Ridder, G.G., Lundblad, R.L., and Pizzo, S.V., Actions of thrombin in the interstitium, Journal of Thrombosis and Haemostasis, 14, 40-47, 2016.

Piizzo, S.V., Lundblad, R.L., and Willis, M.S., Proteolysis in the Interstitial Space, expected, July ,2016